Antidepressant prescribing inequalities in people with comorbid depression and type 2 diabetes: A UK primary care electronic health record study.
<h4>Aims</h4>To compare the likelihood of being prescribed an antidepressant in depressed individuals with and without type 2 diabetes.<h4>Methods</h4>We performed a matched cohort study using primary care record data from the UK Clinical Practice Research Datalink. We used m...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2024-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0309153 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846172721089609728 |
|---|---|
| author | Yutung Ng Joseph F Hayes Annie Jeffery |
| author_facet | Yutung Ng Joseph F Hayes Annie Jeffery |
| author_sort | Yutung Ng |
| collection | DOAJ |
| description | <h4>Aims</h4>To compare the likelihood of being prescribed an antidepressant in depressed individuals with and without type 2 diabetes.<h4>Methods</h4>We performed a matched cohort study using primary care record data from the UK Clinical Practice Research Datalink. We used multivariable logistic regression to compare antidepressant prescribing during the first five years of starting oral antidiabetic medication to a comparison group without type 2 diabetes, matched based on GP practice, age and sex. We performed subgroup analyses stratified by sex, age and ethnicity.<h4>Results</h4>People with type 2 diabetes and depression were 75% less likely to be prescribed an antidepressant compared to people with depression alone (odds ratio (OR) 0.25, 95% confidence interval (CI) 0.25 to 0.26). This difference was greater in males (OR 0.23, 95% CI, 0.22 to 0.24), people older than 56 years (OR 0.23, 95% CI, 0.22 to 0.24), or from a minoritised ethnic background (Asian OR 0.14, 95% CI 0.12-0.14; Black OR 0.12, 95% CI 0.09-0.14).<h4>Conclusions</h4>There may be inequalities in access to antidepressant treatment for people with type 2 diabetes, particularly those who are male, older or from minoritised ethnic backgrounds. |
| format | Article |
| id | doaj-art-1e47b0d7e673494ea6fa0a3d0595eef7 |
| institution | Kabale University |
| issn | 1932-6203 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-1e47b0d7e673494ea6fa0a3d0595eef72024-11-09T05:31:50ZengPublic Library of Science (PLoS)PLoS ONE1932-62032024-01-011911e030915310.1371/journal.pone.0309153Antidepressant prescribing inequalities in people with comorbid depression and type 2 diabetes: A UK primary care electronic health record study.Yutung NgJoseph F HayesAnnie Jeffery<h4>Aims</h4>To compare the likelihood of being prescribed an antidepressant in depressed individuals with and without type 2 diabetes.<h4>Methods</h4>We performed a matched cohort study using primary care record data from the UK Clinical Practice Research Datalink. We used multivariable logistic regression to compare antidepressant prescribing during the first five years of starting oral antidiabetic medication to a comparison group without type 2 diabetes, matched based on GP practice, age and sex. We performed subgroup analyses stratified by sex, age and ethnicity.<h4>Results</h4>People with type 2 diabetes and depression were 75% less likely to be prescribed an antidepressant compared to people with depression alone (odds ratio (OR) 0.25, 95% confidence interval (CI) 0.25 to 0.26). This difference was greater in males (OR 0.23, 95% CI, 0.22 to 0.24), people older than 56 years (OR 0.23, 95% CI, 0.22 to 0.24), or from a minoritised ethnic background (Asian OR 0.14, 95% CI 0.12-0.14; Black OR 0.12, 95% CI 0.09-0.14).<h4>Conclusions</h4>There may be inequalities in access to antidepressant treatment for people with type 2 diabetes, particularly those who are male, older or from minoritised ethnic backgrounds.https://doi.org/10.1371/journal.pone.0309153 |
| spellingShingle | Yutung Ng Joseph F Hayes Annie Jeffery Antidepressant prescribing inequalities in people with comorbid depression and type 2 diabetes: A UK primary care electronic health record study. PLoS ONE |
| title | Antidepressant prescribing inequalities in people with comorbid depression and type 2 diabetes: A UK primary care electronic health record study. |
| title_full | Antidepressant prescribing inequalities in people with comorbid depression and type 2 diabetes: A UK primary care electronic health record study. |
| title_fullStr | Antidepressant prescribing inequalities in people with comorbid depression and type 2 diabetes: A UK primary care electronic health record study. |
| title_full_unstemmed | Antidepressant prescribing inequalities in people with comorbid depression and type 2 diabetes: A UK primary care electronic health record study. |
| title_short | Antidepressant prescribing inequalities in people with comorbid depression and type 2 diabetes: A UK primary care electronic health record study. |
| title_sort | antidepressant prescribing inequalities in people with comorbid depression and type 2 diabetes a uk primary care electronic health record study |
| url | https://doi.org/10.1371/journal.pone.0309153 |
| work_keys_str_mv | AT yutungng antidepressantprescribinginequalitiesinpeoplewithcomorbiddepressionandtype2diabetesaukprimarycareelectronichealthrecordstudy AT josephfhayes antidepressantprescribinginequalitiesinpeoplewithcomorbiddepressionandtype2diabetesaukprimarycareelectronichealthrecordstudy AT anniejeffery antidepressantprescribinginequalitiesinpeoplewithcomorbiddepressionandtype2diabetesaukprimarycareelectronichealthrecordstudy |