Research on uPAR promoting proliferation, migration, and chemoresistance of pancreatic cancer by inhibiting autophagy via MAPK signaling

Background and purpose: Amplification of the urokinase plasminogen activator receptor (uPAR) gene is closely associated with poor prognosis in pancreatic cancer patients. uPAR regulates epithelial-mesenchymal transition (EMT) and chemoresistance in pancreatic cancer cells through the mitogen-activat...

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Bibliographic Details
Main Author: TAN Xiaolang, YAO Sha, WANG Guihua, PENG Luogen
Format: Article
Language:English
Published: Editorial Office of China Oncology 2024-10-01
Series:Zhongguo aizheng zazhi
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Online Access:http://www.china-oncology.com/fileup/1007-3639/PDF/1732079455856-736778426.pdf
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