D-CAPS: an efficient CRISPR-Cas9-based phage defense system for E. coli

D-CAPS: an efficient CRISPR-Cas9-based phage defense system for E. coli

Escherichia coli is widely used in industrial chemical synthesis but faces significant challenges due to bacteriophage contamination, which reduces product quality and yield. Therefore, developing an efficient antiphage system is essential. In this study, we develop a CRISPR-Cas9-based antiphage sys...

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Bibliographic Details
Main Authors: Sun Mingjun, Gao Jie, Tang Hongjie, Wang Hengyi, Zhou Liyan, Song Chuan, Tian Yongqiang, Li Qi
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2025-04-01
Series:Acta Biochimica et Biophysica Sinica
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Keywords: bacteriophage contamination
CRISPR-Cas9
<italic>E</italic>. <italic>coli</italic>
T7 phage
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2024208
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https://www.sciengine.com/doi/10.3724/abbs.2024208

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