Preparation of new doxycycline monohydrate polymorphs by ultrasonication enhanced supercritical antisolvent recrystallization process

Polymorphism is a crucial factor in the pharmaceutical industry, as different polymorphs can display different physicochemical properties, including stability, solubility, and/or bioavailability. The ultrasonication-enhanced supercritical antisolvent recrystallization (UE-SAR) process is a novel inv...

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Bibliographic Details
Main Authors: Snehashis Nandi, Miguel A. Rodrigues, Andreia Duarte, Teresa G. Nunes, Luis Padrela
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Journal of CO2 Utilization
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Online Access:http://www.sciencedirect.com/science/article/pii/S2212982025000666
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