Stiffness and surface topology of silicone implants competitively mediate inflammatory responses of macrophages and foreign body response

Adverse inflammatory responses, dominated by macrophages, that are induced by physical cues of silicone implants can heavily damage the life quality of patients via causing fibrosis and device failure. As stiffness and surface topology affect macrophages at the same time, the competition or partners...

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Bibliographic Details
Main Authors: Sicen He, Qingrong Zhang, Jiezhi Jia, Wei Xia, Shengnan Chen, Fanyi Min, Yanlin Song, Yunlong Yu, Jiangfeng Li, Zheng Li, Gaoxing Luo
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Materials Today Bio
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S259000642400365X
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