The role of bone scintigraphy with single-photon emission computed tomography-computed tomography in the diagnosis and evaluation of calciphylaxis
Calciphylaxis, also known as calcific uremic arteriolopathy, is an uncommon disease, typically found in patients with the end-stage renal disease. Pathophysiological features include small vessel vasculopathy with mural calcification, fibrosis, and thrombosis. The clinical presentation varies but of...
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2017-04-01
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| Series: | World Journal of Nuclear Medicine |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.203076 |
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| author | Patrick Martineau Matthieu Pelletier-Galarneau Sadri Bazarjani |
| author_facet | Patrick Martineau Matthieu Pelletier-Galarneau Sadri Bazarjani |
| author_sort | Patrick Martineau |
| collection | DOAJ |
| description | Calciphylaxis, also known as calcific uremic arteriolopathy, is an uncommon disease, typically found in patients with the end-stage renal disease. Pathophysiological features include small vessel vasculopathy with mural calcification, fibrosis, and thrombosis. The clinical presentation varies but often consists of the necrosis of skin and subcutaneous tissues, with or without visceral organ involvement due to small vessel vasculopathy. This condition has a significant morbidity and mortality, making accurate diagnosis imperative. We present a case of calciphylaxis investigated using planar bone scintigraphy and single-photon emission computed tomography-computed tomography (SPECT-CT). This case stresses the value of SPECT-CT to accurately localize the abnormal uptake in subcutaneous soft tissue microcalcifications and confirms the exact location and extent of pathology. |
| format | Article |
| id | doaj-art-1d3d375d2da74e16adb79a96b31a6ec1 |
| institution | Kabale University |
| issn | 1450-1147 1607-3312 |
| language | English |
| publishDate | 2017-04-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | World Journal of Nuclear Medicine |
| spelling | doaj-art-1d3d375d2da74e16adb79a96b31a6ec12025-08-20T03:48:36ZengThieme Medical and Scientific Publishers Pvt. Ltd.World Journal of Nuclear Medicine1450-11471607-33122017-04-01160217217410.4103/1450-1147.203076The role of bone scintigraphy with single-photon emission computed tomography-computed tomography in the diagnosis and evaluation of calciphylaxisPatrick Martineau0Matthieu Pelletier-Galarneau1Sadri Bazarjani2Department of Nuclear Medicine, University of Ottawa, Ottawa, Ontario, CanadaDepartment of Nuclear Medicine, University of Ottawa, Ottawa, Ontario, CanadaDepartment of Nuclear Medicine, University of Ottawa, Ottawa, Ontario, CanadaCalciphylaxis, also known as calcific uremic arteriolopathy, is an uncommon disease, typically found in patients with the end-stage renal disease. Pathophysiological features include small vessel vasculopathy with mural calcification, fibrosis, and thrombosis. The clinical presentation varies but often consists of the necrosis of skin and subcutaneous tissues, with or without visceral organ involvement due to small vessel vasculopathy. This condition has a significant morbidity and mortality, making accurate diagnosis imperative. We present a case of calciphylaxis investigated using planar bone scintigraphy and single-photon emission computed tomography-computed tomography (SPECT-CT). This case stresses the value of SPECT-CT to accurately localize the abnormal uptake in subcutaneous soft tissue microcalcifications and confirms the exact location and extent of pathology.http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.203076bone scancalciphylaxisheterotopic ossificationhybrid imagingrenal disease |
| spellingShingle | Patrick Martineau Matthieu Pelletier-Galarneau Sadri Bazarjani The role of bone scintigraphy with single-photon emission computed tomography-computed tomography in the diagnosis and evaluation of calciphylaxis World Journal of Nuclear Medicine bone scan calciphylaxis heterotopic ossification hybrid imaging renal disease |
| title | The role of bone scintigraphy with single-photon emission computed tomography-computed tomography in the diagnosis and evaluation of calciphylaxis |
| title_full | The role of bone scintigraphy with single-photon emission computed tomography-computed tomography in the diagnosis and evaluation of calciphylaxis |
| title_fullStr | The role of bone scintigraphy with single-photon emission computed tomography-computed tomography in the diagnosis and evaluation of calciphylaxis |
| title_full_unstemmed | The role of bone scintigraphy with single-photon emission computed tomography-computed tomography in the diagnosis and evaluation of calciphylaxis |
| title_short | The role of bone scintigraphy with single-photon emission computed tomography-computed tomography in the diagnosis and evaluation of calciphylaxis |
| title_sort | role of bone scintigraphy with single photon emission computed tomography computed tomography in the diagnosis and evaluation of calciphylaxis |
| topic | bone scan calciphylaxis heterotopic ossification hybrid imaging renal disease |
| url | http://www.thieme-connect.de/DOI/DOI?10.4103/1450-1147.203076 |
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