PIVKA-II but not dp-ucMGP is associated with aortic calcification in chronic kidney disease
Abstract Background Patients with chronic kidney disease (CKD) are susceptible to vascular calcification and vitamin K deficiency. Matrix gla protein (MGP) is a potent inhibitor of calcification requiring vitamin K for activation. Inactive MGP, i.e. dephosphorylated uncarboxylated MGP (dp-ucMGP), is...
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Main Authors: | Jakob Nyvad, Kent Lodberg Christensen, Gratien Andersen, Mark Reinhard, Bjarne Linde Nørgaard, Jonna Skov Madsen, Sebastian Nielsen, Martin Bjergskov Thomsen, Jesper Møller Jensen, Christian Daugaard Peters, Niels Henrik Buus |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-11-01
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Series: | BMC Nephrology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12882-024-03876-5 |
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