Spontaneous Regression of Plasmablastic Lymphoma in an Immunocompetent Patient: Case Report and Review of the Literature
Plasmablastic lymphoma (PBL) is a rare and highly aggressive type of lymphoma, which is commonly associated with human immunodeficiency virus (HIV) infection. Spontaneous regression of aggressive lymphomas is rare as they typically require administration of chemotherapy and radiotherapy for treatmen...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2022/1142049 |
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| _version_ | 1849307125489074176 |
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| author | Kee Tat Lee Nurul Akmar Misron Norasmidar Abdul Aziz Chin Hau Wong Hong Keng Liew |
| author_facet | Kee Tat Lee Nurul Akmar Misron Norasmidar Abdul Aziz Chin Hau Wong Hong Keng Liew |
| author_sort | Kee Tat Lee |
| collection | DOAJ |
| description | Plasmablastic lymphoma (PBL) is a rare and highly aggressive type of lymphoma, which is commonly associated with human immunodeficiency virus (HIV) infection. Spontaneous regression of aggressive lymphomas is rare as they typically require administration of chemotherapy and radiotherapy for treatment. Here, we describe a case of a spontaneous regression of PBL after nasal biopsy and computed tomography (CT) guided biopsy of paravertebral mass in an immunocompetent patient. We postulate that the patient’s immune system may be activated as a result of the stress and physical trauma brought on by nasal and paravertebral mass biopsy. Our case highlights the rare phenomenon of spontaneous regression of lymphoma which needs to be further studied on to establish its underlying pathophysiology. |
| format | Article |
| id | doaj-art-1cfa80cbbdf44e759fd8eceb3e72230a |
| institution | Kabale University |
| issn | 2090-6579 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-1cfa80cbbdf44e759fd8eceb3e72230a2025-08-20T03:54:51ZengWileyCase Reports in Hematology2090-65792022-01-01202210.1155/2022/1142049Spontaneous Regression of Plasmablastic Lymphoma in an Immunocompetent Patient: Case Report and Review of the LiteratureKee Tat Lee0Nurul Akmar Misron1Norasmidar Abdul Aziz2Chin Hau Wong3Hong Keng Liew4Department of MedicineDepartment of PathologyDepartment of MedicineDepartment of MedicineDepartment of MedicinePlasmablastic lymphoma (PBL) is a rare and highly aggressive type of lymphoma, which is commonly associated with human immunodeficiency virus (HIV) infection. Spontaneous regression of aggressive lymphomas is rare as they typically require administration of chemotherapy and radiotherapy for treatment. Here, we describe a case of a spontaneous regression of PBL after nasal biopsy and computed tomography (CT) guided biopsy of paravertebral mass in an immunocompetent patient. We postulate that the patient’s immune system may be activated as a result of the stress and physical trauma brought on by nasal and paravertebral mass biopsy. Our case highlights the rare phenomenon of spontaneous regression of lymphoma which needs to be further studied on to establish its underlying pathophysiology.http://dx.doi.org/10.1155/2022/1142049 |
| spellingShingle | Kee Tat Lee Nurul Akmar Misron Norasmidar Abdul Aziz Chin Hau Wong Hong Keng Liew Spontaneous Regression of Plasmablastic Lymphoma in an Immunocompetent Patient: Case Report and Review of the Literature Case Reports in Hematology |
| title | Spontaneous Regression of Plasmablastic Lymphoma in an Immunocompetent Patient: Case Report and Review of the Literature |
| title_full | Spontaneous Regression of Plasmablastic Lymphoma in an Immunocompetent Patient: Case Report and Review of the Literature |
| title_fullStr | Spontaneous Regression of Plasmablastic Lymphoma in an Immunocompetent Patient: Case Report and Review of the Literature |
| title_full_unstemmed | Spontaneous Regression of Plasmablastic Lymphoma in an Immunocompetent Patient: Case Report and Review of the Literature |
| title_short | Spontaneous Regression of Plasmablastic Lymphoma in an Immunocompetent Patient: Case Report and Review of the Literature |
| title_sort | spontaneous regression of plasmablastic lymphoma in an immunocompetent patient case report and review of the literature |
| url | http://dx.doi.org/10.1155/2022/1142049 |
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