CRISPR-based functional genomics tools in vertebrate models

Abstract The advent of CRISPR–Cas technologies has revolutionized functional genomics by enabling precise genetic manipulations in various model organisms. In popular vertebrate models, including mice and zebrafish, CRISPR has been adapted to high-throughput mutagenesis workflows, knock-in alleles a...

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Bibliographic Details
Main Authors: Gaurav K. Varshney, Shawn M. Burgess
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-025-01514-0
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