Regulatory interaction between metabolite transporters coordinates glucose and exometabolite fluxes to drive bioenergetics

Abstract The composition of tricarboxylic acid cycle metabolites in the external environment of cells determines vital physiological functions, including nutrient and mineral absorption, inflammation, and cellular energy management. Here, we study how the transport of external metabolites into the c...

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Bibliographic Details
Main Authors: Noa Yehoshua, Ahlam Khamaysi, Liana Shimshilashvili, Aharon Keshet, Mahmoud Taha, Moran Fremder, Hadar Eini-Rider, Ehud Ohana
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62103-3
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