Toll-like receptor 2 activation of early divided bovine embryo promotes its viability and development competence in vitro

Toll-like receptor 2 activation of early divided bovine embryo promotes its viability and development competence in vitro

Abstract Improving the quality and developmental competence of in vitro-produced (IVP) embryos is crucial for assisted reproductive technologies. Recently, we demonstrated that TLR2, an innate immune receptor, is expressed in bovine sperm and their activation improves fertilization and subsequent em...

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Bibliographic Details
Main Authors: Dongxue Ma, Ihshan Akthar, Taiyo Hashimoto, Mohamed A. Marey, Kazuya Kusama, Kazuhiko Imakawa, Masayuki Shimada, Akio Miyamoto
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
TLR2 activation
Embryo development
Calcium
Autophagy
In vitro
Online Access:https://doi.org/10.1038/s41598-025-09570-2
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https://doi.org/10.1038/s41598-025-09570-2

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