Methylglyoxal impairs human dermal fibroblast survival and migration by altering RAGE-hTERT mRNA expression in vitro

Methylglyoxal impairs human dermal fibroblast survival and migration by altering RAGE-hTERT mRNA expression in vitro

Fibroblasts are native residents in dermal layer of human skin which are important for dermal regeneration and essential during cutaneous wound healing by releasing inflammatory markers and actively migrate to close an open wound. Premature skin ageing due to methylglyoxal (MGO) has recently caught...

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Bibliographic Details
Main Authors: Nurul Muhammad Prakoso, Ayu Mulia Sundari, Fadhilah, Abinawanto, Anantya Pustimbara, Astari Dwiranti, Anom Bowolaksono
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Toxicology Reports
Subjects:
Human dermal fibroblasts
Methylglyoxal
Reactive oxygen species
Dermal toxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S221475002400218X
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