A Role for PPAR𝛽/𝛿 in Ocular Angiogenesis

The uses of highly selective PPAR𝛽/𝛿 ligands and PPAR𝛽/𝛿 knockout mice have shown a direct ability of PPAR𝛽/𝛿 to regulate angiogenesis in vitro and in vivo in animal models. PPAR𝛽/𝛿 ligands induce the proangiogenic growth factor VEGF in many cells and tissues, though its actions in the eye are not k...

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Bibliographic Details
Main Author: David Bishop-Bailey
Format: Article
Language:English
Published: Wiley 2008-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2008/825970
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