Health-related quality of life in a large cohort of patients with cardiac implantable electronic devices A registry-based study.
<h4>Aim</h4>The association of cardiac implantable electronic devices (CIED), namely pacemaker (PM), implantable cardioverter-defibrillator (ICD) and cardiac resynchronization therapy with (CRT-D) or without defibrillator (CRT-P) with health-related quality of life (HRQoL) is lacking.<...
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Public Library of Science (PLoS)
2024-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0314978 |
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| author | Paolo Gatti Carolin Nymark Fredrik Gadler |
| author_facet | Paolo Gatti Carolin Nymark Fredrik Gadler |
| author_sort | Paolo Gatti |
| collection | DOAJ |
| description | <h4>Aim</h4>The association of cardiac implantable electronic devices (CIED), namely pacemaker (PM), implantable cardioverter-defibrillator (ICD) and cardiac resynchronization therapy with (CRT-D) or without defibrillator (CRT-P) with health-related quality of life (HRQoL) is lacking.<h4>Methods and results</h4>Data from the Swedish Pacemaker and ICD Registry collected from January 2019 to February 2022 was used to analyze the responses to the European Quality of Life-5 Dimension questionnaire (EQ-5D) before and after one year of the CIED implant. Descriptive analysis was performed using Pearson's chi-square test, the analysis of variance ANOVA, the Kruskal-Wallis test and Wilcoxon signed-rank test when appropriate. A multivariable regression analysis was used to compare the EQ-5D index and EQ-VAS variation after 1 year. Of 1,479 who completed the EQ-5D, 80% had a PM, 10% an ICD, 5% a CRT-P and 6% a CRT-D. The median age was 77 years with females constituting 38% of the PM group and 17% of the ICD group. The EQ-VAS and the EQ-5D index significantly increased after one year from the PM and CRT-P implant (EQ-VAS +2.8, standard deviations (SD) 23 and +5.8, SD 24.9; EQ-5D index +0.019, SD 0.114 and +0.051, SD 0.125) while only the EQ-5D index increased after one year from the ICD implant (+0.002, SD 0.104). After adjusting for age, sex and HRQoL at baseline, the presence of defibrillator was associated with lower EQ-VAS (ICD EQ-VAS variation: -3.4, 95% confidence intervals (CI) -6.7; -0.1 and CRT-D EQ-VAS variation -4.8, 95% CI -8.8;-0.7) and EQ-5D index (ICD EQ-5D index variation: -0.018, 95% CI -0.035; -0.0003 and CRT-D EQ-5D index variation -0.025 95% CI 0.046;0.004) after one year compared to PM.<h4>Conclusion</h4>These findings, showing the HRQoL associated with CIED, are important to support physicians' and pacemaker nurses' care after device implantation by embracing the patients' perspectives. |
| format | Article |
| id | doaj-art-1bccf39a577b49f4a5bf461c5e318552 |
| institution | Kabale University |
| issn | 1932-6203 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Public Library of Science (PLoS) |
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| series | PLoS ONE |
| spelling | doaj-art-1bccf39a577b49f4a5bf461c5e3185522025-01-08T05:32:43ZengPublic Library of Science (PLoS)PLoS ONE1932-62032024-01-011912e031497810.1371/journal.pone.0314978Health-related quality of life in a large cohort of patients with cardiac implantable electronic devices A registry-based study.Paolo GattiCarolin NymarkFredrik Gadler<h4>Aim</h4>The association of cardiac implantable electronic devices (CIED), namely pacemaker (PM), implantable cardioverter-defibrillator (ICD) and cardiac resynchronization therapy with (CRT-D) or without defibrillator (CRT-P) with health-related quality of life (HRQoL) is lacking.<h4>Methods and results</h4>Data from the Swedish Pacemaker and ICD Registry collected from January 2019 to February 2022 was used to analyze the responses to the European Quality of Life-5 Dimension questionnaire (EQ-5D) before and after one year of the CIED implant. Descriptive analysis was performed using Pearson's chi-square test, the analysis of variance ANOVA, the Kruskal-Wallis test and Wilcoxon signed-rank test when appropriate. A multivariable regression analysis was used to compare the EQ-5D index and EQ-VAS variation after 1 year. Of 1,479 who completed the EQ-5D, 80% had a PM, 10% an ICD, 5% a CRT-P and 6% a CRT-D. The median age was 77 years with females constituting 38% of the PM group and 17% of the ICD group. The EQ-VAS and the EQ-5D index significantly increased after one year from the PM and CRT-P implant (EQ-VAS +2.8, standard deviations (SD) 23 and +5.8, SD 24.9; EQ-5D index +0.019, SD 0.114 and +0.051, SD 0.125) while only the EQ-5D index increased after one year from the ICD implant (+0.002, SD 0.104). After adjusting for age, sex and HRQoL at baseline, the presence of defibrillator was associated with lower EQ-VAS (ICD EQ-VAS variation: -3.4, 95% confidence intervals (CI) -6.7; -0.1 and CRT-D EQ-VAS variation -4.8, 95% CI -8.8;-0.7) and EQ-5D index (ICD EQ-5D index variation: -0.018, 95% CI -0.035; -0.0003 and CRT-D EQ-5D index variation -0.025 95% CI 0.046;0.004) after one year compared to PM.<h4>Conclusion</h4>These findings, showing the HRQoL associated with CIED, are important to support physicians' and pacemaker nurses' care after device implantation by embracing the patients' perspectives.https://doi.org/10.1371/journal.pone.0314978 |
| spellingShingle | Paolo Gatti Carolin Nymark Fredrik Gadler Health-related quality of life in a large cohort of patients with cardiac implantable electronic devices A registry-based study. PLoS ONE |
| title | Health-related quality of life in a large cohort of patients with cardiac implantable electronic devices A registry-based study. |
| title_full | Health-related quality of life in a large cohort of patients with cardiac implantable electronic devices A registry-based study. |
| title_fullStr | Health-related quality of life in a large cohort of patients with cardiac implantable electronic devices A registry-based study. |
| title_full_unstemmed | Health-related quality of life in a large cohort of patients with cardiac implantable electronic devices A registry-based study. |
| title_short | Health-related quality of life in a large cohort of patients with cardiac implantable electronic devices A registry-based study. |
| title_sort | health related quality of life in a large cohort of patients with cardiac implantable electronic devices a registry based study |
| url | https://doi.org/10.1371/journal.pone.0314978 |
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