Optimizing midlife metabolic syndrome thresholds for dementia: a prospective study of two UK population-based cohorts

Optimizing midlife metabolic syndrome thresholds for dementia: a prospective study of two UK population-based cohorts

Abstract Background The concept of metabolic syndrome (MetS) was developed to identify individuals at higher risk of type 2 diabetes and cardiovascular disease, but its relevance for dementia remains unclear. We examined MetS in midlife for association with late-onset dementia, focusing on the thres...

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Bibliographic Details
Main Authors: Sam Vidil, Archana Singh-Manoux, Benjamin Landré, Aurore Fayosse, Séverine Sabia, Marcos D. Machado-Fragua
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Alzheimer’s Research & Therapy
Subjects:
Cardiometabolic risk factors
Metabolic syndrome
Optimal thresholds
Dementia
Midlife
Online Access:https://doi.org/10.1186/s13195-025-01732-8
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