Design, synthesis, and carbonic anhydrase inhibition activities of Schiff bases incorporating benzenesulfonamide scaffold: Molecular docking application
In this study, The inhibitory actions of human carbonic anhydrase (CA, EC 4.2.1.1) (hCA) isoforms I, II, IX, and XII are being examined using recently synthesized substituted hydroxyl Schiff derivatives based on the quinazoline scaffold 4–22. Quinazolines 2, 3, 4, 5, 7, 10, 15, and 18 reduce the act...
Saved in:
| Main Authors: | Adel S. El-Azab, Alaa A.-M. Abdel-Aziz, Silvia Bua, Alessio Nocentini, Ahmed H. Bakheit, Hamad M. Alkahtani, Mohamed M. Hefnawy, Claudiu T. Supuran |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2023-12-01
|
| Series: | Saudi Pharmaceutical Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1319016423003614 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The Value of CA125 and CA19-9 in the Diagnosis of Stage Ⅲ and Ⅳ Endometriosis
by: Wenwen Zhang, et al.
Published: (2024-02-01) -
Calcium Allocation to the Tree Canopy and the Edible Part of Sweet Cherry Fruit Is Hindered by Boron Soil Deficiency
by: Claudia Bonomelli, et al.
Published: (2025-03-01) -
Synthesis, spectral characterization, thermo-kinetic and biological studies of some complexes derived from tridentate hydrazone Schiff base
by: Gajanan Dongare, et al.
Published: (2021-10-01) -
Ponderación de la información generada en la Estación Experimental Agropecuaria Oliveros del INTA (INTA EEA Oliveros) mediante el proceso analítico jerárquico
by: G.C. RÓTOLO, et al.
Published: (2016-01-01) -
Ammonia removal from simulated fish farms by metal organic framework ingrained by egg shell and fish bones
by: Ebtehal A. H. Gamal, et al.
Published: (2025-05-01)