Microfluidic nanobubbles produced using a micromixer for ultrasound imaging and gene delivery

Abstract Ultrasound (US)-mediated delivery is considered relatively safe and achieves tissue-specific targeting by simply adjusting the application site of the physical energy. Moreover, combining US with micro- or nanobubbles (MBs or NBs), which serve as US contrast agents, enhances the delivery of...

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Bibliographic Details
Main Authors: Taiki Yamaguchi, Yoko Endo-Takahashi, Kento Awaji, Seiyo Numazawa, Yuni Onishi, Rui Tada, Mitsuo Ogasawara, Yoshimasa Takizawa, Hitoshi Kurumizaka, Yoichi Negishi
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-99171-w
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