ALDH2 Inhibition Potentiates High Glucose Stress-Induced Injury in Cultured Cardiomyocytes

Aldehyde dehydrogenase (ALDH) gene superfamily consists of 19 isozymes. They are present in various organs and involved in metabolizing aldehydes that are biologically generated. For instance, ALDH2, a cardiac mitochondrial ALDH isozyme, is known to detoxify 4-hydroxy-2-nonenal, a reactive aldehyde...

Full description

Saved in:
Bibliographic Details
Main Authors: Guodong Pan, Mandar Deshpande, Rajarajan A. Thandavarayan, Suresh Selvaraj Palaniyandi
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2016/1390861
Tags: Add Tag
No Tags, Be the first to tag this record!