$Successful Treatment of Refractory Graft-Versus-Host Disease with Ruxolitinib in a Child after Autologous Stem Cell Transplantation$

Successful Treatment of Refractory Graft-Versus-Host Disease with Ruxolitinib in a Child after Autologous Stem Cell Transplantation

Autologous hematopoietic stem cell transplantation (AHSCT) is an increasingly used curative treatment for some solid tumors in children. Instead of allogeneic transplantation, the risk of developing graft-versus-host disease (GvHD) is much lower after AHSCT. Although the clinical findings of auto-GV...

Full description

Saved in:

Bibliographic Details
Main Authors:	Nurşah Eker, Burcu Tufan Taş, Ömer Doğru, Emel Şenay, Ayşe Gülnur Tokuç, Ahmet Koç
Format:	Article
Language:	English
Published:	Galenos Publishing House 2022-06-01
Series:	Journal of Pediatric Research
Subjects:	autologous stem cell transplantation children graft versus host disease ruxolitinib steroid-resistant
Online Access:	http://jpedres.org/archives/archive-detail/article-preview/successful-treatment-of-refractory-graft-versus-ho/52013
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Retrospective analysis of ruxolitinib as induction treatment in pediatric hemophagocytic lymphohistiocytosis
by: Shu-yi Guo, et al.
Published: (2025-12-01)

Ruxolitinib Has a Protective Effect on Ovarian and Endometrial Tissues in Diabetic Rats via STAT3 Pathway
by: Savaş Özdemir, et al.
Published: (2024-09-01)

Double Infection in a Patient with Chronic GVHD Post Allogeneic Transplant: “Hickam's Dictum” Trumps “Occam's Razor”!—A Case Report with Review of Literature
by: Fen Saj, et al.

Case Report: Successful treatment of steroid- and ruxolitinib-refractory gastrointestinal acute graft-versus-Host disease with anti-thymocyte globulin
by: Lulu Zhang, et al.
Published: (2025-07-01)

Leukocytoclastic vasculitis in JAK2-positive essential thrombocythemia: a case of cytokine-driven urticarial rash responsive to ruxolitinib
by: Murad Aldarayseh, et al.
Published: (2025-07-01)

Regulatory T-cells and allogeneic hematopoietic stem cell transplantation
by: O. S. Karavaeva, et al.
Published: (2022-12-01)

Reduced morbidity and mortality of cGVHD in patients who received treatment with mesenchymal stromal cells for steroid-resistant aGVHD: long-term follow-up of a randomized phase 3 trial
by: Ke Zhao, et al.
Published: (2025-07-01)

Restricting SLC7A5-mediated Leucine uptake in T cells prevents acute GVHD and maintains GVT response
by: Nieves Fernández-Gallego, et al.
Published: (2025-05-01)

JAK/STAT inhibition protects glucocorticoid receptor knockout mice from lethal malaria-induced hypoglycemia and hyperinflammation
by: Fran Prenen, et al.
Published: (2025-07-01)

Autologous collagen-induced chondrogenesis with high tibial osteotomy for large collapsed steroid-induced osteonecrosis in a patient with systemic lupus erythematosus: a case report and literature review
by: Dong Hwan Lee, et al.
Published: (2025-07-01)

LYMPHOPENIA AS A FACTOR INVOLVED IN THE AUTOIMMUNITY DEVELOPMENT IN MURINE GRAFT VS. HOST DISEASE
by: E. V. Goiman, et al.
Published: (2012-05-01)

Age-Related Differences in the Clinical Patterns of Ocular Graft-Versus-Host Disease
by: Rana Altan-Yaycıoğlu, et al.
Published: (2022-12-01)

Autologous Peripheral Blood-Derived Orthobiologics for the Management of Elbow Disorders: A Review of Current Clinical Evidence
by: Ashim Gupta, et al.
Published: (2025-01-01)

The late outcomes of syngeneic hematopoietic stem cell transplantation in patients with blood disorders
by: A. A. Dmitrova, et al.
Published: (2022-11-01)

Analysis of the short-to-intermediate-term efficacy of autologous costochondral transplantation in treatment for Hepple V osteochondral lesion of talus
by: Jiazheng Wang, et al.
Published: (2025-08-01)

Autologous serum supplementation promotes the phenotype maintenance of human chondrocytes with increased cellular autophagy
by: Wei Yin, et al.
Published: (2025-03-01)

Variants of storage and perioperative use of autologous blood components
by: Yu. S. Bocharova, et al.
Published: (2013-02-01)

Genomic profile helps to predict the clonal evolution and outcome of BCR-ABL-negative myeloproliferative neoplasms
by: Xiaodong Guo, et al.
Published: (2025-08-01)

Two oral verrucous carcinomas in a patient with oral graft vs. host disease– recurrent verrucous carcinoma: a case report
by: Jiaqi Huang, et al.
Published: (2025-07-01)

Clinical Features of Cutaneous Acute Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cells Transplantation in Children with Hemato-Oncological Diseases
by: Tatiana S. Belysheva, et al.
Published: (2020-12-01)

Three resected cases of esophageal carcinoma considered as being secondary solid tumors after bone marrow transplantation
by: Yamato Ninomiya, et al.
Published: (2021-03-01)

Extracorporeal photopheresis in the treatment of graft-versus-host disease
by: I. V. Guz, et al.
Published: (2016-03-01)

Decreased frequency and inflammatory change of FoxP3+ regulatory T cells in immunopathogenesis of human acute graft-versus-host disease
by: Nayeon Seong, et al.
Published: (2025-07-01)

Graft conditioning with fluticasone propionate reduces graft‐versus‐host disease upon allogeneic hematopoietic cell transplantation in mice
by: Erika S Varady, et al.
Published: (2023-08-01)

Myeloid dendritic cells in peripheral blood correlate with the occurrence of acute graft-versus-host disease
by: Qianqian Wang, et al.
Published: (2025-07-01)

The rise of exosome-mediated mechanisms in MSC therapy
by: Weihua Liu, et al.
Published: (2025-07-01)

Clinical application of preoperative autologous blood donation under anesthesia monitoring
by: DU Chunhong, et al.
Published: (2025-05-01)

CLINICAL EFFECTIVENESS OF HIGH-DOSE IMMUNOSUPPRESSIVE THERAPY WITH AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION IN MULTIPLE SCLEROSIS PATIENTS
by: D. A. Fedorenko, et al.
Published: (2014-12-01)

Treatment of refractory chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation with low-dose interleukin-2
by: I. S. Moiseev, et al.
Published: (2015-12-01)

Anti-monocyte globulin in allogeneic transplantation of hematopoietic stem cells
by: Yu. R. Zalyalov, et al.
Published: (2022-11-01)

The MICA‐129 dimorphism affects NKG2D signaling and outcome of hematopoietic stem cell transplantation
by: Antje Isernhagen, et al.
Published: (2015-10-01)

Documents to procure gamma irradiation chamber and license for operation in blood center
by: Rakesh Kumar Luhar, et al.
Published: (2025-07-01)

Surgery of cicatricial stage of choroidal neovascular membrane with autologous conditioned plasma
by: D. G. Arsyutov
Published: (2022-01-01)

Autologous serum eye drops for treatment of dry eye syndrome
by: Sheikh Saiful Islam Shaheen, et al.
Published: (2024-06-01)

Autologous serum eye drops for treatment of dry eye syndrome
by: Sheikh Saiful Islam Shaheen, et al.
Published: (2024-06-01)

Application of autologous hemopoietic stem cells in inoperable patients with chronic critical lower limb ischemia
by: I. P. Mikhaylov, et al.
Published: (2022-04-01)

Clinical and Functional Results of the Use of Suspension of Autologous Mononuclear Leucocytes in the Surgical Treatment of Bullous Keratopathy
by: M. S. Denisko, et al.
Published: (2022-10-01)

Experience of successful autologous hematopoietic stem cell transplantation in patients with an unfavorable prognosis of systemic scleroderma
by: V. I. Mazurov, et al.
Published: (2022-07-01)

INTRACORONARY AUTOLOGOUS BONE MARROW STEM CELL THERAPY IN DIASTOLIC HEART FAILURE
by: V. I. Shumakov, et al.
Published: (2009-06-01)

Autologous emulsified fat injection for rejuvenation of scars: A prospective observational study
by: Lekshmi S. Bhooshan, et al.
Published: (2018-01-01)