Integrative metagenomic, transcriptomic, and proteomic analysis reveal the microbiota-host interplay in early-stage lung adenocarcinoma among non-smokers

Integrative metagenomic, transcriptomic, and proteomic analysis reveal the microbiota-host interplay in early-stage lung adenocarcinoma among non-smokers

Abstract Background The incidence of early-stage lung adenocarcinoma (ES-LUAD) is steadily increasing among non-smokers. Previous research has identified dysbiosis in the gut microbiota of patients with lung cancer. However, the local microbial profile of non-smokers with ES-LUAD remains largely unk...

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Bibliographic Details
Main Authors: Yaohui Sun, Zhiming Gan, Xiaojin Wang, Jian Liu, Wei Zhong, Zhiyan Zhang, Jiebin Zuo, Hang Zhong, Xiuting Huang, Zhixiang Yan, Qingdong Cao
Format: Article
Language:English
Published: BMC 2024-07-01
Series:Journal of Translational Medicine
Subjects:
ES-LUAD
Intratumoral microbiome
Multi-omics
Correlation analysis
Non-invasive diagnosis
Online Access:https://doi.org/10.1186/s12967-024-05485-0
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https://doi.org/10.1186/s12967-024-05485-0

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