The Struggle Between Chimeric Antigen Receptor T-Cell Therapy and Neurological Complications in Acute Lymphoblastic Leukemia Treatment

The Struggle Between Chimeric Antigen Receptor T-Cell Therapy and Neurological Complications in Acute Lymphoblastic Leukemia Treatment

Acute lymphoblastic leukemia (ALL) accounts for approximately 25% of childhood cancers and 20% of leukemia cases in adults, with a higher prevalence in males than females. It is characterized by symptoms such as fatigue, fever, and bone pain and poses a significant risk of mortality if left untreate...

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Bibliographic Details
Main Authors: Norwin Kubick, Marzena Łazarczyk, Omar Awad, Michał Ławiński, Jarosław Olav Horbańczuk, Mariusz Sacharczuk, Atanas G. Atanasov, Piotr Religa, Michel Edwar Mickael
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Current Issues in Molecular Biology
Subjects:
CAR T-cell therapy
acute lymphoblastic leukemia
immunotherapy
cytokine release syndrome
Online Access:https://www.mdpi.com/1467-3045/47/5/381
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