Microwave Activation: Solventless Catalysed Synthesis of Cross Conjugated Dienones of Tropinone

Microwave Activation: Solventless Catalysed Synthesis of Cross Conjugated Dienones of Tropinone

Cross-conjugated dienones are very important biologically active products. The condensation of N-methyl-8-azabicyclo[3.2.1]-bicyclo[3.2.1]octan-3-one (tropinone) with aromatic aldehydes takes place in the presence of acidic (K10 clay, silica) or basic catalysts (alumina, KF-alumina). The best yields...

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Bibliographic Details
Main Authors: Renata Gasparova, Didier Villemin, Nathalie Bar
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Chemistry Proceedings
Subjects:
cross-conjugated dienones
tropinone
microwave
clay catalysis
KF-alumina
Online Access:https://www.mdpi.com/2673-4583/14/1/28
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