Investigating the effect of femtosecond laser pulses on noscapine and curcumin cellular uptake and improving drug delivery in gastric cancer cells

Investigating the effect of femtosecond laser pulses on noscapine and curcumin cellular uptake and improving drug delivery in gastric cancer cells

The MKN45 cell line, a type of gastric cancer cell, exhibits resistance to chemotherapy agents through various mechanisms. Curcumin and noscapine, two plant-derived anticancer compounds, exhibit selective cytotoxicity towards cancer cells. However, their bioavailability is poor both in vitro and in...

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Bibliographic Details
Main Authors: Nastaran Kahrarian, Hossein Behboudi, Atoosa Sadat Arabanian, Abolfazl Abedi, Reza Massudi
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Heliyon
Subjects:
Femtosecond laser pulse
MKN45 cells
MTT test
Trypan blue
Curcumin and noscapine
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024172015
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