Nuclear factor erythroid 2-related factor 1 regulates the expression of proteasomal genes in ketotic cows and protects mammary cells against free fatty acid–induced endoplasmic reticulum stress

ABSTRACT: Ketosis is a common metabolic disorder in high-yielding cows and is characterized by high concentrations of BHB and free fatty acids (FFA). High concentrations of FFA induce endoplasmic reticulum (ER) stress in multiple organs including mammary tissue, and result in reduced milk production...

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Bibliographic Details
Main Authors: Taiyu Shen, Shijie Xia, Muhammad Usman, Xinyi Xu, Juan J. Loor, Chuang Xu
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Journal of Dairy Science
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022030224011792
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