TOPK promotes immune suppression in kidney renal clear cell carcinoma and emerges as a prognostic and therapeutic target
Abstract The T-LAK cell-originated protein kinase (TOPK) has been associated with poor prognosis in various cancers, yet its specific role in kidney renal clear cell carcinoma (KIRC) remains unclear. In this study, we conducted a comprehensive investigation of TOPK expression and its association wit...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
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| Series: | BMC Cancer |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12885-025-14665-0 |
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