Pharmacogenetic study of antipsychotic–induced lipid and BMI changes in Chinese schizophrenia patients: A Genome-Wide Association Study

Pharmacogenetic study of antipsychotic–induced lipid and BMI changes in Chinese schizophrenia patients: A Genome-Wide Association Study

Abstract Second-generation antipsychotics (SGAs) are widely used to treat schizophrenia (SCZ), but they often induce metabolic side effects like dyslipidemia and obesity. We conducted genome-wide association studies (GWASs) to identify genetic variants associated with SGA-induced lipid and BMI chang...

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Main Authors: Kenneth Chi-Yin Wong, Perry Bok-Man Leung, Benedict Ka-Wa Lee, Zoe Zi-Yu Zheng, Emily Man-Wah Tsang, Meng-Hui Liu, Kelly Wing-Kwan Lee, Shi-Tao Rao, Pak-Chung Sham, Simon Sai-Yu Lui, Hon-Cheong So
Format: Article
Language:English
Published: Nature Publishing Group 2025-08-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-025-03499-w
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https://doi.org/10.1038/s41398-025-03499-w

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