Bone marrow mesenchymal stem cell‐derived exosomes improve renal fibrosis by reducing the polarisation of M1 and M2 macrophages through the activation of EP2 receptors

Bone marrow mesenchymal stem cell‐derived exosomes improve renal fibrosis by reducing the polarisation of M1 and M2 macrophages through the activation of EP2 receptors

Abstract Renal fibrosis is the pathological outcome of most end‐stage renal diseases, yet there are still limited therapeutic options for it. In recent years, bone marrow mesenchymal stem cell‐derived exosomes (BM‐MSCs) have received much attention. Here, we investigate the therapeutic effect of BM‐...

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Bibliographic Details
Main Authors: Yuqing Lu, Lulu Yang, Xiao Chen, Jing Liu, Anqi Nie, Xiaolan Chen
Format: Article
Language:English
Published: Wiley 2022-02-01
Series:IET Nanobiotechnology
Subjects:
EP2
exosome
macrophage polarisation
mesenchymal stem cell
Online Access:https://doi.org/10.1049/nbt2.12071
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