Tangeretin alleviates sepsis-induced acute lung injury by inhibiting ferroptosis of macrophage via Nrf2 signaling pathway

Tangeretin alleviates sepsis-induced acute lung injury by inhibiting ferroptosis of macrophage via Nrf2 signaling pathway

Abstract Background Sepsis-induced acute lung injury (ALI) is a severe clinical condition accompanied with high mortality. Tangeretin, which is widely found in citrus fruits, has been reported to exert antioxidant and anti-inflammatory properties. However, whether tangeretin protects against sepsis-...

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Bibliographic Details
Main Authors: Hui Zhang, Yan Wang, Shenghua Wang, Xiaomei Xue, Kai Huang, Dunfeng Xu, Lai Jiang, Siyuan Li, Yunqian Zhang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Chinese Medicine
Subjects:
Tangeretin
Sepsis
Acute lung injury
Ferroptosis
Nrf2
Online Access:https://doi.org/10.1186/s13020-025-01063-8
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