Proteomic profiling of peripheral blood mononuclear cells reveals immune dysregulation and metabolic alterations in kidney transplant recipients with COVID-19

Proteomic profiling of peripheral blood mononuclear cells reveals immune dysregulation and metabolic alterations in kidney transplant recipients with COVID-19

The COVID-19 pandemic has significantly impacted global health, especially in vulnerable populations like kidney transplant recipients (KTRs). Recently, mass spectrometry-based proteomics has emerged as a powerful tool to shed light on a broad spectrum of dysregulated biological processes in KTRs wi...

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Bibliographic Details
Main Authors: Giuseppe G. F. Leite, Mônica Bragança Sousa, Larissa de Oliveira C. P. Rodrigues, Milena Karina Colo Brunialti, José Medina-Pestana, Joe M. Butler, Hessel Peters-Sengers, Lúcio Requião-Moura, Reinaldo Salomão
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
acute kidney injury
KTRs
mass spectrometry
PBMC
SARS-CoV-2
systems biology
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1508110/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1508110/full

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