Nab-paclitaxel plus cisplatin versus gemcitabine plus cisplatin as first-line treatment in advanced biliary tract cancer: results of a multicentre, randomised, phase II trial

Nab-paclitaxel plus cisplatin versus gemcitabine plus cisplatin as first-line treatment in advanced biliary tract cancer: results of a multicentre, randomised, phase II trial

Abstract Background The efficacy and safety of conventional first-line chemotherapeutic regimens for the treatment of advanced biliary tract carcinomas (ABTCs) have been unsatisfactory. Objectives We aimed to explore alternative chemotherapeutic regimens capable of providing improved efficacy and fe...

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Main Authors: Xiao Yang, Yu-Hong Dai, Hui Peng, Ming-Sheng Zhang, Qiang Fu, Shun-Fang Liu, Li Sun, Yan-Mei Zou, Hai-Sheng Xu, Ping Qiu, Hong Qiu, Qiao Huang, Heng-hui Cheng, Liang Zhuang
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Cancer
Subjects:
Biliary tract carcinomas
Advanced stage
Chemotherapy
Albumin-paclitaxel
First-line treatment
Cisplatin
Online Access:https://doi.org/10.1186/s12885-025-14581-3
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https://doi.org/10.1186/s12885-025-14581-3

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