Is the myonuclear domain ceiling hypothesis dead?
Muscle fibres are multinuclear cells, and the cytoplasmic territory where a single myonucleus controls transcriptional activity is called the myonuclear domain (MND). MND size shows flexibility during muscle hypertrophy. The MND ceiling hypothesis states that hypertrophy results in the expansion of...
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Main Authors: | Ferdos Aman, Eman El Khatib, Alanood AlNeaimi, Ahmed Mohamed, Alya Sultan Almulla, Amna Zaidan, Jana Alshafei, Omar Habbal, Salma Eldesouki, Rizwan Qaisar |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer – Medknow Publications
2023-07-01
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Series: | Singapore Medical Journal |
Subjects: | |
Online Access: | https://journals.lww.com/10.11622/smedj.2021103 |
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