Redox Imbalance and Antioxidant Defenses Dysfunction: Key Contributors to Early Aging in Childhood Cancer Survivors

Redox Imbalance and Antioxidant Defenses Dysfunction: Key Contributors to Early Aging in Childhood Cancer Survivors

Survival rates for childhood cancer survivors (CCS) have improved, although they display a risk for early frailty due to the long-term effects of chemo/radiotherapy, including early aging. This study investigates antioxidant defenses and oxidative damage in mononuclear cells (MNCs) from CCS, compari...

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Bibliographic Details
Main Authors: Vanessa Cossu, Nadia Bertola, Chiara Fresia, Federica Sabatini, Silvia Ravera
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Antioxidants
Subjects:
aging
antioxidant defenses
childhood cancer survivors
Nrf2
oxidative phosphorylation
oxidative stress
Online Access:https://www.mdpi.com/2076-3921/13/11/1397
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