Cell-Cycle-Related and Expression Elevated Protein in Tumor Upregulates the Antioxidant Genes via Activation of NF-κB/Nrf2 in Acute Liver Injury

Cell-Cycle-Related and Expression Elevated Protein in Tumor Upregulates the Antioxidant Genes via Activation of NF-κB/Nrf2 in Acute Liver Injury

Background and aims: Cell-cycle-related and expression elevated protein in tumor (CREPT, also named RPRD1B) is highly expressed in tumors and functions to promote tumorigenesis. However, the role of CREPT in the pathophysiology of acute liver injury is limited. Here, we demonstrate that CREPT plays...

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Bibliographic Details
Main Authors: Minghan Wang, Bin Wu, Kaiyang Tang, Xuexin Wang, Xinyan Liu, Yinan Duan, Jiayu Wang, Xiaoguang Wang, Yinyin Wang, Jun Li, Chenxi Cao, Fangli Ren, Zhijie Chang
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Toxics
Subjects:
acute liver injury
CREPT
oxidative stress
NF-κB/Nrf2
Online Access:https://www.mdpi.com/2305-6304/12/12/893
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