High-Yield Synthesis of <i>N</i><sup>4</sup>-(3-Chloro-4-fluorophenyl)-7-((4-methoxybenzyl)thio)quinazoline-4,6-diamine via <i>N</i>-(3-Chloro-4-fluorophenyl)-7-((4-methoxybenzyl)thio)-6-nitroquinazolin-4-amine
The target compound, <i>N</i><sup>4</sup>-(3-chloro-4-fluorophenyl)-7-((4-methoxybenzyl)thio)quinazoline-4,6-diamine, was synthesized in two steps from <i>N</i>-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine by a nucleophilic aromatic substitution, y...
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| Main Authors: | Susila Thapa, Jeanne L. Bolliger |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-01-01
|
| Series: | Molbank |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-8599/2025/1/M1958 |
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