WCN24-1234 RENAL TUBULE-SPECIFIC NRF2 DELETION ATTENUATES GLOMERULAR HYPERFILTRATION AND KIDNEY INJURY VIA DOWN-REGULATION OF SGLT2 AND ANGIOTENSINOGEN EXPRESSION IN DIABETIC MICE

WCN24-1234 RENAL TUBULE-SPECIFIC NRF2 DELETION ATTENUATES GLOMERULAR HYPERFILTRATION AND KIDNEY INJURY VIA DOWN-REGULATION OF SGLT2 AND ANGIOTENSINOGEN EXPRESSION IN DIABETIC MICE

Saved in:

Bibliographic Details
Main Authors:	John Chan, Ke Su, shuiling zhao, Wen-Xia Yang, Junzheng Peng, Kana Miyata, Janos Filep, Julie Ingelfinger, Shao-Ling Zhang
Format:	Article
Language:	English
Published:	Elsevier 2024-04-01
Series:	Kidney International Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S2468024924005515
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Synthesis of <i>N</i>-Flurbiprofen-Substituted 1,2,3,4-Tetrahydroisoquinolines
by: Diyana Dimitrova, et al.
Published: (2024-05-01)

Urinary Angiotensinogen Could Be a Prognostic Marker of Renoprotective Effects of Alogliptin in Patients with Type 2 Diabetes
by: Tomoko Mizushige, et al.
Published: (2015-01-01)

Ertugliflozin, a SGLT-2 Inhibitor, Guards Against Thioacetamide-induced Liver Fibrosis: The Nrf2/HO-1 and TLR4/ TGF-β1 Pathways
by: Nourhan Hassan, et al.
Published: (2025-07-01)

The Effects of CO2 Laser with or without Nanohydroxyapatite Paste in the Occlusion of Dentinal Tubules
by: Mohammed Abbood Al-maliky, et al.
Published: (2014-01-01)

Mechanism of substrate recognition and release of human SGLT2
by: Wenhao Cui, et al.
Published: (2025-08-01)

Role of SGLT2 inhibitors in the treatment of visceral obesity
by: M. A. Druzhilov, et al.
Published: (2021-02-01)

Crystal structure of 1-(1-chloroethyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolinium chloride
by: Ziroat E. Urunbaeva, et al.
Published: (2024-12-01)

KIF2C Deletion Causes Meiotic Abnormalities and Nonobstructive Azoospermia in Mice
by: Hiroaki Kitakaze, et al.
Published: (2025-01-01)

A retrospective analysis of combination therapy with GLP-1 receptor agonists and SGLT2 inhibitors versus SGLT2 inhibitor monotherapy in patients with MASLD
by: Jheng-Yan Wu, et al.
Published: (2025-08-01)

Targeting conformational changes in C‐reactive protein to inhibit pro‐inflammatory actions
by: János G Filep
Published: (2022-12-01)

Double vulnerability of active-NRF2 lung squamous cell carcinoma to NRF2 and TRIM24
by: Miriam Sánchez-Ortega, et al.
Published: (2025-07-01)

The Effect of Hyperfiltration on Kidney Function in Living Donor Kidney Transplantation: A Prospective Cohort Study
by: Maruhum Bonar H. Marbun, et al.
Published: (2020-10-01)

Renal hyperfiltration as risk factor of major adverse cardiovascular events in patients with acute myocardial infarction
by: Jin Sug Kim, et al.
Published: (2025-07-01)

The Effect of Hyperfiltration on Kidney Function in Living Donor Kidney Transplantation: A Prospective Cohort Study
by: Maruhum Bonar H. Marbun, et al.
Published: (2020-10-01)

Synthesis and Crystal Structure of Two Nitro-Regioisomers of cis-4(4- Methoxyphenyl)-3-Methyl-2-Phenyl-1,2,3,4-Tetrahydroquinoline
by: Arnold R. Romero Bohórquez, et al.
Published: (2013-04-01)

Cystic Dilation of the Aqueductus Sylvii in Case of Trisomy 17p11.2—pter with the Deletion of the Terminal Portion of the Chromosome 6
by: Emese Horváth, et al.
Published: (2010-01-01)

Association of angiotensinogen and angiotensin II receptor type I polymorphisms with biomarkers of carbohydrate and lipid metabolism in Dagestan residents with type 2 diabetes and hypertension
by: M. Z. Saidov, et al.
Published: (2021-11-01)

The outcomes of SGLT-2 inhibitor utilization in diabetic kidney transplant recipients
by: Jia-Yuh Sheu, et al.
Published: (2024-11-01)

Ketoacidosis as unexpected adverse reaction SGLT<sub>2</sub> inhibitor
by: T. M. Bukatina, et al.
Published: (2018-02-01)

SGLT2 Inhibitor Treatment Is Associated With Reduced Cardiac Glucose Metabolism
by: Brett W. Sperry, MD, et al.
Published: (2025-08-01)

Progress in studies on renal effects and molecular mechanism of SGLT-2 inhibitors
by: XING Bei, et al.
Published: (2020-01-01)

Position of SGLT2i in prediabetes: A systematic review of literature
by: Kaushik Biswas, et al.
Published: (2025-04-01)

SGLT2 inhibition mitigates intracerebral hemorrhage risk by modulating inflammation
by: Mingsheng Huang, et al.
Published: (2025-05-01)

Role of NF-E2 related factor 2 (Nrf2) on chemotherapy resistance in acute myeloid leukemia (AML) and the effect of pharmacological inhibition of Nrf2.
by: Sreeja Karathedath, et al.
Published: (2017-01-01)

Horizontal Outer Retinal Tubulations in Healed Choroiditis
by: Mousumi Banerjee, et al.
Published: (2025-04-01)

Circulating Levels of Angiotensinogen, Sex Hormones, and Hormone Therapy—The Multi‐Ethnic Study of Atherosclerosis (MESA)
by: Karita C. F. Lidani, et al.
Published: (2025-06-01)

The role of SGLT2 inhibitors beyond glucose-lowering to cardio-renal protection
by: J. Karalliedde
Published: (2021-04-01)

SGLT2 inhibitors and kidneys: mechanisms and main effects in diabetes mellitus patients
by: Vladimir V Salukhov, et al.
Published: (2021-01-01)

The expanding role of SGLT2 inhibitors beyond glucose-lowering to cardiorenal protection
by: Emily Brown, et al.
Published: (2021-01-01)

SGLT2 Inhibitors: From Molecular Mechanisms to Clinical Outcomes in Cardiology and Diabetology
by: Marlena Stielow, et al.
Published: (2025-07-01)

Impact of SGLT2i on Cardiac Remodeling and the Soleus Muscle of Infarcted Rats
by: Lidiane Moreira Souza, et al.
Published: (2025-05-01)

Effect of new water-soluble phenolic antioxidants on the activity of Nrf2-driven enzymes, glutathione system, and Nrf2 translocation into the nucleus
by: E. B. Menshchikova, et al.
Published: (2020-12-01)

Proximal Tubule Cell Hypothesis for Cardiorenal Syndrome in Diabetes
by: Akihiko Saito, et al.
Published: (2011-01-01)

Age-related retinopathy in NRF2-deficient mice.
by: Zhenyang Zhao, et al.
Published: (2011-04-01)

The effects of SGLT2i on cardiac metabolism in patients with HFpEF: Fact or fiction?
by: Francesca Cinti, et al.
Published: (2025-05-01)

Case Reports That Illustrate the Efficacy of SGLT2 Inhibitors in the Type 1 Diabetic Patient
by: David S. H. Bell
Published: (2015-01-01)

Effects of Heat Transfer Characteristics of R32 and R1234yf with Al2O3 Nanoparticle through U-Bend Tube Evaporator
by: Latifur Islam, et al.
Published: (2024-01-01)

Compatibility of Eco-Friendly Gas-Insulated Medium HFO-1234ze(E) with Copper and Aluminum
by: Song Xiao, et al.
Published: (2025-01-01)

Optimization of in vivo delivery methods and their applications in seminiferous tubules of mice
by: Xinyuan Dai, et al.
Published: (2025-08-01)

Elucidating the Role of Nrf2 Signaling Pathway in Mycoplasma Infections
by: Sarmistha Saha, et al.
Published: (2025-03-01)