Revised model for cell cycle regulation by iron: differential roles between transferrin and ferritin

Revised model for cell cycle regulation by iron: differential roles between transferrin and ferritin

Iron is essential for neoplasms including natural killer (NK) cell lymphoma, and mainly supplemented by transferrin and stored by ferritin. Although accumulating studies had demonstrated that iron chelation arrests cell cycle progression at G1 phase, our previous studies showed the induction of DNA...

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Bibliographic Details
Main Authors: Ryo Yanagiya, Hiroko Kato, Akinori Ninomiya, Masaya Ueno, Akane Kanamori, Yuji Miyatake, Masahiro Oka, Keisuke Ishii, Tadashi Matsuura, So Nakagawa, Atsushi Hirao, Makoto Onizuka, Ai Kotani
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Redox Biology
Subjects:
Iron
Transferrin
Cell cycle
S phase arrest
Nascent DNA synthesis
Mitochondria
Online Access:http://www.sciencedirect.com/science/article/pii/S221323172500240X
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