Pioneer: a synthetic human antibody phage display library for rapid therapeutic lead generation

Pioneer: a synthetic human antibody phage display library for rapid therapeutic lead generation

Antibody phage display, a biotechnological method for selecting fully human antibodies from diverse libraries, is firmly established in antibody drug discovery due to its speed and flexibility. In this study, we introduce Pioneer, one of the largest synthetic human antibody libraries developed to da...

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Bibliographic Details
Main Authors: Mateusz Putyrski, Christian Hentrich, Manuel Cavada, Melissa Wich, Sarah-Jane Kellmann, Sarah Hanselka, Michaela Eick-Werner, Hanh Hanuschka, Waldemar Preis, Christina Werkmeister, Martina Klee, Achim Knappik, Francisco Ylera
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:mAbs
Subjects:
Phage display
SpyCatcher
fab antibody library
SpyTag
SpyDisplay
high-affinity antibodies
Online Access:https://www.tandfonline.com/doi/10.1080/19420862.2025.2543769
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https://www.tandfonline.com/doi/10.1080/19420862.2025.2543769

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