A pan-cancer analysis of homeobox family: expression characteristics and latent significance in prognosis and immune microenvironment

A pan-cancer analysis of homeobox family: expression characteristics and latent significance in prognosis and immune microenvironment

BackgroundThe Homeobox (HOX) gene family are conserved transcription factors that are essential for embryonic development, oncogenesis, and cancer suppression in biological beings. Abnormally expressed HOX genes in cancers are directly associated with prognosis.MethodsPublic databases such as TCGA a...

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Bibliographic Details
Main Authors: Yuanhui Wang, Jie Gao, Ziyi Ren, Ziyi Shen, Wei Gu, Qinyi Miao, Xiaomeng Hu, Yan Wu, Wei Liu, Jia Jia, Yi Cai, Chunpeng (Craig) Wan, Lei Sun, Tingdong Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Oncology
Subjects:
Homeobox family
pan-cancer
immune microenvironment
prognosis
HOXB7
HOXC6
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1521652/full
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