Exploration of shared pathogenic factors and causative genes in early-stage endometrial cancer and osteoarthritis

Exploration of shared pathogenic factors and causative genes in early-stage endometrial cancer and osteoarthritis

Abstract Osteoarthritis (OA) has been implicated in the development and progression of early-stage endometrial cancer (EC), suggesting shared pathogenic factors between the two diseases. This study aimed to investigate the causal relationship between OA and EC and to identify causative genes common...

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Bibliographic Details
Main Authors: Yiyun Bai, Sang Luo, Ruzhen Shuai, Xiaomei Zhang, Liwei Yuan, Dan Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Mendelian randomization
Osteoarthritis
Endometrial cancer
Enrichment analysis
Nomogram
Online Access:https://doi.org/10.1038/s41598-025-04470-x
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https://doi.org/10.1038/s41598-025-04470-x

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