Protocol for the generation and immunostaining of thick murine lung tissue slices

Summary: Precision-cut lung slices (PCLSs) largely preserve the native structural and cellular complexity of the lung, enabling detailed spatial analysis of resident cell populations. Here, we present a protocol for generating PCLSs from mouse lungs for subsequent immunofluorescent staining to detec...

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Bibliographic Details
Main Authors: Ali Khadim, Mahtab Shahriari Felordi, Hawlader Sabbir Hasan, Georgios Kiliaris, Mahsa Zabihi, Hannah Hofmann, Elie El Agha
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:STAR Protocols
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Online Access:http://www.sciencedirect.com/science/article/pii/S266616672500440X
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