Inhibition of Sema4D/PlexinB1 signaling alleviates vascular dysfunction in diabetic retinopathy

Inhibition of Sema4D/PlexinB1 signaling alleviates vascular dysfunction in diabetic retinopathy

Abstract Diabetic retinopathy (DR) is a common complication of diabetes and leads to blindness. Anti‐VEGF is a primary treatment for DR. Its therapeutic effect is limited in non‐ or poor responders despite frequent injections. By performing a comprehensive analysis of the semaphorins family, we iden...

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Main Authors: Jie‐hong Wu, Ya‐nan Li, An‐qi Chen, Can‐dong Hong, Chun‐lin Zhang, Hai‐ling Wang, Yi‐fan Zhou, Peng‐Cheng Li, Yong Wang, Ling Mao, Yuan‐peng Xia, Quan‐wei He, Hui‐juan Jin, Zhen‐yu Yue, Bo Hu
Format: Article
Language:English
Published: Springer Nature 2020-01-01
Series:EMBO Molecular Medicine
Subjects:
diabetic retinopathy
mDIA1
N‐cadherin
Sema4D
Online Access:https://doi.org/10.15252/emmm.201810154
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https://doi.org/10.15252/emmm.201810154

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