Screening of some isoxazole derivatives as plausible inhibitors of E. coli: a computational and synthetic approach

Abstract Novel isoxazole-based analogues were rationally designed and subjected to virtual screening via in-silico methodologies, with the objective of identifying potential anti-Escherichia coli agents targeting key enzymes implicated in the microorganism’s metabolism and proliferation. Molecular d...

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Bibliographic Details
Main Authors: Judy Jays, Saravanan Janardhanan
Format: Article
Language:English
Published: Springer 2025-06-01
Series:Discover Chemistry
Subjects:
Online Access:https://doi.org/10.1007/s44371-025-00210-2
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