EXT1 as an Independent Prognostic Biomarker in Breast Cancer: Its Correlation with Immune Infiltration and Clinicopathological Parameters

EXT1 as an Independent Prognostic Biomarker in Breast Cancer: Its Correlation with Immune Infiltration and Clinicopathological Parameters

Exostosin 1 (EXT1) encodes a type II transmembrane glycosyltransferase residing in the endoplasmic reticulum and plays an essential role in the elongation of heparan sulfate chain biosynthesis. Additionally, EXT1 may act as an oncogene that could promote cell proliferation as well as cancer cell met...

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Bibliographic Details
Main Authors: Amira Hossny, Hatem A. F. M. Hassan, Sherif Ashraf Fahmy, Hazem Abdelazim, Mahmoud Mohamed Kamel, Ahmed H. Osman, Sherif Abdelaziz Ibrahim
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Immuno
Subjects:
exostosin 1 (EXT1)
breast cancer
prognosis
immune infiltration
Online Access:https://www.mdpi.com/2673-5601/5/1/1
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