Iodine Deficiency Exacerbates Thyroidal and Neurological Effects of Developmental Perchlorate Exposure in the Neonatal and Adult Rat

Iodine Deficiency Exacerbates Thyroidal and Neurological Effects of Developmental Perchlorate Exposure in the Neonatal and Adult Rat

Thyroid hormones (THs) require iodine for biosynthesis and play critical roles in brain development. Perchlorate is an environmental contaminant that reduces serum THs by blocking the uptake of iodine from the blood to the thyroid gland. Using a pregnant rodent model, we examined the impact of mater...

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Bibliographic Details
Main Authors: Mary E. Gilbert, MaryAnn G. Hawks, Kiersten S. Bell, Wendy Oshiro, Carmen Wood, Barbara Jane George, Ryne Thomas, Jermaine Ford
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Toxics
Subjects:
perchlorate
brain
development
neurotoxicity
thyroid hormone
iodine deficiency
Online Access:https://www.mdpi.com/2305-6304/12/12/842
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https://www.mdpi.com/2305-6304/12/12/842

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