Physical and Chemical Properties of an Enzymolysis Peptide of Peony Flower and Beneficial Effect on Skin Health

The enzymolysis peptide of peony flower was studied herein to promote the development and utilization of this flower. The molecular weight distribution and amino acid composition of the peptide were analyzed, and the beneficial effects of the peptide were studied by assessing their ability to inhibi...

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Main Authors: Beibei ZENG, Jing LÜ, Xingru LU, Wenbo ZHI, Daigen LI
Format: Article
Language:zho
Published: The editorial department of Science and Technology of Food Industry 2024-11-01
Series:Shipin gongye ke-ji
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Online Access:http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2023110278
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author Beibei ZENG
Jing LÜ
Xingru LU
Wenbo ZHI
Daigen LI
author_facet Beibei ZENG
Jing LÜ
Xingru LU
Wenbo ZHI
Daigen LI
author_sort Beibei ZENG
collection DOAJ
description The enzymolysis peptide of peony flower was studied herein to promote the development and utilization of this flower. The molecular weight distribution and amino acid composition of the peptide were analyzed, and the beneficial effects of the peptide were studied by assessing their ability to inhibit tyrosinase activity, advanced glycation end products (AGEs) formation, and hyaluronidase in vitro. The in vitro results were further verified in a zebrafish melanin accumulation model, results indicated that the active peptide was a small molecule comprising 15 amino acids, with an average molecular weight of 644 Da. At 10 mg/mL, the respective in vitro inhibition rates for tyrosinase activity, AGEs formation, and hyaluronidase were 88.96%, 90.50%, and 60.43%, respectively. The respective DPPH (2,2-diphenyl-1-picrylhydrazyl) and hydroxyl free radical scavenging rates were 74.77% and 94.74%, respectively. The zebrafish model studies revealed a melanin inhibition rate of 40.59% when the sample concentration was 1000 μg/mL. In conclusion, the results of these in vivo and in vitro studies preliminarily indicate that the peony flower enzymolysis peptide can potentially improve skin health.
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publishDate 2024-11-01
publisher The editorial department of Science and Technology of Food Industry
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series Shipin gongye ke-ji
spelling doaj-art-13ed79e3785d4dbabe6fbf9adcadbe1b2024-11-22T07:28:26ZzhoThe editorial department of Science and Technology of Food IndustryShipin gongye ke-ji1002-03062024-11-01452231432110.13386/j.issn1002-0306.20231102782023110278-22Physical and Chemical Properties of an Enzymolysis Peptide of Peony Flower and Beneficial Effect on Skin HealthBeibei ZENG0Jing LÜ1Xingru LU2Wenbo ZHI3Daigen LI4Xiamen Yuanzhidao Biotechnology Co., Ltd., Xiamen 361100, ChinaXiamen Yuanzhidao Biotechnology Co., Ltd., Xiamen 361100, ChinaXiamen Yuanzhidao Biotechnology Co., Ltd., Xiamen 361100, ChinaXiamen Yuanzhidao Biotechnology Co., Ltd., Xiamen 361100, ChinaXiamen Yuanzhidao Biotechnology Co., Ltd., Xiamen 361100, ChinaThe enzymolysis peptide of peony flower was studied herein to promote the development and utilization of this flower. The molecular weight distribution and amino acid composition of the peptide were analyzed, and the beneficial effects of the peptide were studied by assessing their ability to inhibit tyrosinase activity, advanced glycation end products (AGEs) formation, and hyaluronidase in vitro. The in vitro results were further verified in a zebrafish melanin accumulation model, results indicated that the active peptide was a small molecule comprising 15 amino acids, with an average molecular weight of 644 Da. At 10 mg/mL, the respective in vitro inhibition rates for tyrosinase activity, AGEs formation, and hyaluronidase were 88.96%, 90.50%, and 60.43%, respectively. The respective DPPH (2,2-diphenyl-1-picrylhydrazyl) and hydroxyl free radical scavenging rates were 74.77% and 94.74%, respectively. The zebrafish model studies revealed a melanin inhibition rate of 40.59% when the sample concentration was 1000 μg/mL. In conclusion, the results of these in vivo and in vitro studies preliminarily indicate that the peony flower enzymolysis peptide can potentially improve skin health.http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2023110278peony flower enzymolysis peptidewhitening effecthealthy skinanti-oxidationzebrafish
spellingShingle Beibei ZENG
Jing LÜ
Xingru LU
Wenbo ZHI
Daigen LI
Physical and Chemical Properties of an Enzymolysis Peptide of Peony Flower and Beneficial Effect on Skin Health
Shipin gongye ke-ji
peony flower enzymolysis peptide
whitening effect
healthy skin
anti-oxidation
zebrafish
title Physical and Chemical Properties of an Enzymolysis Peptide of Peony Flower and Beneficial Effect on Skin Health
title_full Physical and Chemical Properties of an Enzymolysis Peptide of Peony Flower and Beneficial Effect on Skin Health
title_fullStr Physical and Chemical Properties of an Enzymolysis Peptide of Peony Flower and Beneficial Effect on Skin Health
title_full_unstemmed Physical and Chemical Properties of an Enzymolysis Peptide of Peony Flower and Beneficial Effect on Skin Health
title_short Physical and Chemical Properties of an Enzymolysis Peptide of Peony Flower and Beneficial Effect on Skin Health
title_sort physical and chemical properties of an enzymolysis peptide of peony flower and beneficial effect on skin health
topic peony flower enzymolysis peptide
whitening effect
healthy skin
anti-oxidation
zebrafish
url http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2023110278
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AT xingrulu physicalandchemicalpropertiesofanenzymolysispeptideofpeonyflowerandbeneficialeffectonskinhealth
AT wenbozhi physicalandchemicalpropertiesofanenzymolysispeptideofpeonyflowerandbeneficialeffectonskinhealth
AT daigenli physicalandchemicalpropertiesofanenzymolysispeptideofpeonyflowerandbeneficialeffectonskinhealth