Neuroprotective effects and mechanisms of osteocalcin in an Alzheimer’s disease cell model

Neuroprotective effects and mechanisms of osteocalcin in an Alzheimer’s disease cell model

Objective‍　‍To explore the neuroprotective effects of osteocalcin (OCN) on an Alzheimer’s disease (AD) cell model and its potential mechanisms, providing a scientific basis for new therapeutic targets for AD. Methods‍　‍Human neuroblastoma cell line SH-SY5Y was treated with 40 nmol/L okadaic acid (OA...

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Bibliographic Details
Main Authors: FANG Lilin, ZHU Qifeng, ZHANG Mingda
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2025-08-01
Series:陆军军医大学学报
Subjects:
osteocalcin
alzheimer’s disease
tau hyperphosphorylation
cell apoptosis
akt/mtor
Online Access:http://aammt.tmmu.edu.cn/html/202504118.html
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