Clearing Amyloid-Beta by Astrocytes: The Role of Rho GTPases Signaling Pathways as Potential Therapeutic Targets

Astrocytes, vital support cells in the central nervous system (CNS), are crucial for maintaining neuronal health. In neurodegenerative diseases such as Alzheimer’s disease (AD), astrocytes play a key role in clearing toxic amyloid-β (Aβ) peptides. Aβ, a potent neuroinflammatory trigger, stimulates a...

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Bibliographic Details
Main Authors: Gyeongah Park, Zhen Jin, Hui Lu, Jianyang Du
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/14/12/1239
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