Novel Ser74 of NF-κB/IκBα phosphorylated by MAPK/ERK regulates temperature adaptation in oysters

Novel Ser74 of NF-κB/IκBα phosphorylated by MAPK/ERK regulates temperature adaptation in oysters

Abstract Phosphorylation of Ser32 and Ser36 controls the degradation of IκBα is the conserved cascade mechanisms of immune core signaling pathway, NF-κB pathway in metazoans, but it’s response to abiotic stress and the presence of novel phosphorylation mechanisms in other species remain unclear. Her...

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Main Authors: Chaogang Wang, Zhuxiang Jiang, Mingyang Du, Rihao Cong, Wei Wang, Taiping Zhang, Jincheng Chen, Guofan Zhang, Li Li
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Cell Communication and Signaling
Subjects:
NF-κB pathway
MAPK pathway
IκBα
ERK
Temperature Adaptation
Oysters
Online Access:https://doi.org/10.1186/s12964-024-01923-0
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https://doi.org/10.1186/s12964-024-01923-0

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