CD8 T cell dynamics and immune cell trafficking in ZIKV infection: implications for neuroinflammation and therapy

Abstract The 2015–2016 Zika virus (ZIKV) epidemic underscored the severe consequences of congenital Zika syndrome (CZS) and the broader challenges posed by neurotropic flaviviruses. As key mediators of cytotoxic immunity, CD8 T cells play a crucial and multifaceted role in ZIKV pathogenesis. While e...

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Bibliographic Details
Main Author: Sungjun Park
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Virology Journal
Subjects:
Online Access:https://doi.org/10.1186/s12985-025-02866-9
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