Central nervous system vascularization in human embryos and neural organoids

Summary: In recent years, neural organoids derived from human pluripotent stem cells (hPSCs) have offered a transformative pre-clinical platform for understanding central nervous system (CNS) development, disease, drug effects, and toxicology. CNS vasculature plays an important role in all these sce...

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Bibliographic Details
Main Authors: Sarah M. Boutom, Teresa P. Silva, Sean P. Palecek, Eric V. Shusta, Tiago G. Fernandes, Randolph S. Ashton
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Cell Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724014190
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